Dynamic brain network states in human generalized spike-wave discharges
نویسندگان
چکیده
منابع مشابه
Generalized spike-wave discharges involve a default mode network in patients with juvenile absence epilepsy: a MEG study.
This study uses magnetoencephalography (MEG) to examine whether cortical regions that constitute a default mode network are involved during generalized spike-wave discharges (GSWs) in patients with juvenile absence epilepsy (JAE). We studied five JAE patients for whom MEG was recorded using a 204-channel, whole-head gradiometer system. Dynamic statistical parametric mapping (dSPM) was done to e...
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Unlike focal or partial epilepsy, which has a confined range of influence, idiopathic generalized epilepsy (IGE) often affects the whole or a larger portion of the brain without obvious, known cause. It is important to understand the underlying network which generates epileptic activity and through which epileptic activity propagates. The aim of the present study was to investigate the thalamoc...
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INTRODUCTION Different studies have investigated by means of EEG-fMRI coregistration the brain networks related to generalized spike-and-wave discharges (GSWD) in patients with idiopathic generalized epilepsy (IGE). These studies revealed a widespread GSWD-related neural network that involves the thalamus and regions of the default mode network. In this study we investigated which brain regions...
متن کاملSpike-wave discharges and sleep spindles in rats.
Sleep spindles and spike-wave discharges are thought to originate from the same thalamic pacemaker. In the present work it is investigated whether sleep spindles and spike-wave discharges are also sensitive for the same drugs. Adult male WAG/Rij rats were chronically implanted with frontal and occipital EEG electrode pairs. Rats were intraperitoneally injected with clonidine (0.00625 mg/kg), ph...
متن کاملSpike-wave discharges and sleep spindles in rats
Sleep spindles and spike-wave discharges are thought to originate from the same thalamic pacemaker. In the present work it is investigated whether sleep spindles and spike-wave discharges are also sensitive for the same drugs. Adult male WAGIRij rats were chronically implanted with frontal and occipital EEG electrode pairs. Rats were intraperitoneally injected with clonidine (0.00625 mgkg), phe...
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ژورنال
عنوان ژورنال: Brain
سال: 2018
ISSN: 0006-8950,1460-2156
DOI: 10.1093/brain/awy223